ICSI Treatment in Mumbai: What Is It?
Intracytoplasmic Sperm Injection is known as ICSI. To help in fertilization, a single sperm is injected into an egg during this therapy. Patients with sperm-related problems include those who have:
- Extremely low sperm count
- Sperm are atypical or non-motile;
- IVF was tried in the past but proved unsuccessful.
From the first consultation to the post-procedure care, Bloom IVF’s skilled team offers complete assistance throughout the ICSI process, doing all possible to maximize the likelihood of a good outcome. Bloom IVF is a top option for those looking for cutting-edge reproductive options because of its commitment to quality and a patient-centered approach.
ICSI Procedure Step by Step
1. Stimulation of the Ovaries
- Objective: to encourage the ovaries to release a large number of eggs.
- Medication: Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) injections are the first step in the procedure. GnRH agonists and antagonists are occasionally used to stop early ovulation.
- Monitoring: To track the growth of new follicles and hormone levels, the patient receives frequent blood tests and ultrasounds throughout this stage. This aids in figuring out the best time to retrieve eggs.
2. Egg Retrieval
- Timing: If the ultrasound findings indicate mature follicles, the egg retrieval is planned accordingly.
- Procedure: A transvaginal ultrasound-guided needle is injected into the ovaries through the vaginal wall while the patient is sedated or under general anesthesia.
- Aspiration: To extract the eggs and aspirate (suction out) the follicles, a needle is utilized. After aspirating the fluid, the eggs are identified and recovered in the laboratory.
- Post-Retrieval: Following the procedure, individuals could have light cramps or spotting. Usually, painkillers are given if needed.
3. Sperm Collection
- Preparation: On the day of egg retrieval, sperm is taken from the donor or the male partner. Usually, ejaculating into a sterile container accomplishes this.
- Processing: To extract the sperm from the seminal fluid, the sperm sample is treated in a lab. The healthiest sperm are isolated using procedures like swim-up techniques or density gradient centrifugation.
- Evaluation: The motility, morphology, and concentration of the sperm are evaluated. For the injection procedure, only the most viable sperm are chosen.
4. Sperm Injection
- Preparation: The chosen sperm is rendered immobile and made ready for injection.
- Injection: A thin glass needle is used to extract a single sperm under a microscope. The sperm is injected straight into the egg’s cytoplasm by puncturing the egg’s outer membrane with a second needle.
- Accuracy: This method necessitates high accuracy to guarantee that the sperm is properly inserted into the egg. A high-magnification micromanipulation apparatus is used to carry it out.
5. Fertilisation and Embryo Culture
- Monitoring: After injection, eggs are checked for evidence of fertilization. Usually, this is seen within a day.
- Development: To replicate the environment of the human body, fertilized eggs, or embryos, are cultivated in a specialized incubator. For three to five days, depending on the technique, the embryos are observed for cell division and development.
6. Embryo Transfer
- Selection: The quality and developmental stage of the embryos are evaluated. Only the finest embryos are chosen to be transferred.
- Method: To transfer an embryo, a tiny catheter is passed through the cervix and into the uterus. After that, the chosen embryo or embryos are inserted into the uterus.
- Guidance: To guarantee precise embryo implantation and to guide the catheter, ultrasound imaging may be utilized.
- Following the transfer, patients could have light cramps or spotting. For this portion of the surgery, anesthesia is usually not needed.
7. Luteal Phase Support
- Goal: To increase the likelihood of embryo implantation by providing support for the uterine lining.
- Drugs: Hormonal drugs can be injected, taken orally, orally vaginally, generally as progesterone supplements. They facilitate the implantation of embryos and sustain the uterine lining.
8. Pregnancy Testing
- Timing: To ascertain whether implantation has taken place and a pregnancy has been established, a pregnancy test (often a blood test) is performed 10-14 days following the embryo transfer.
- Follow-Up: If the test results are positive, an ultrasound is planned to track the progress of the pregnancy. If the test yields unfavorable results, more cycles or conversations about the future steps are taken into consideration.
9. After-Procedure Care
- Monitoring: Patients are instructed to keep an eye out for any indications of difficulties, like intense cramping or heavy bleeding, and to get in touch with their clinic if anything goes wrong.
- Lifestyle: Advice is given on how to lead a healthy lifestyle and steer clear of behaviors that might affect the results of the treatment.
This precise ICSI procedure step by step covers all parts of the technique, from ovarian stimulation to post-operative care. Every stage needs to be carefully executed and closely monitored to ensure the greatest possible result. Also Read: ICSI Cost in India.
Conclusion
The ICSI procedure step by step reveals the intricate process that can significantly enhance fertilization rates for couples dealing with male infertility issues. ICSI is a useful method used in IVF treatment that helps couples with male infertility problems such as low sperm count, poor motility, or failed IVF cycles achieve much higher fertilization rates. ICSI gives a better likelihood of successful fertilization than traditional IVF, but it does not ensure pregnancy.
Speak with a licensed fertility clinic like Bloom IVF about your circumstances and the best course of action if you’re thinking about ICSI. With its cutting-edge reproductive technologies and individualized care, Bloom IVF is at the forefront of reproductive medicine. Their knowledgeable staff offers complete assistance during the ICSI procedure, increasing the likelihood of success and facilitating a more seamless experience for couples looking to begin or grow their family.